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KMID : 0363220070450010076
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Korean Journal of Dermatology
2007 Volume.45 No. 1 p.76 ~ p.78
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High Dose UVA-1 Phototherapy for Morphea
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Suh Kee-Suck
Lee Jin-Woo
Roh Hyo-Jin
Choi Soo-Young
Doh Ki-Seung
Kim Sang-Tae
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Abstract
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Morphea is a rare, sclerotic connective tissue disorder and is thought to be caused by a decreased collagenase activity. Numerous treatment modalities have been tried, such as infiltration with glucocorticosteroid, D-penicillamine, antimalarial agents and cyclosporine. However, all have shown only limited success. We report a case of a 21 year- old female with localized scleroderma, who showed a marked improvement after localized therapy with high dose UVA-1.
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KEYWORD
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Collagenase 1, High dose UVA-1, Morphea
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